Sepsis
Why it Matters?
Researchers at the National Institute of Technology (NIT) Calicut have developed a portable, low-cost electrochemical biosensor for rapid point-of-care (POC) detection of sepsis using endotoxin as a biomarker.
What You Should Know?
Sepsis is a life-threatening medical emergency caused by the body’s dysregulated immune response to infection, leading to widespread inflammation, organ dysfunction, and potentially death.
Sepsis is most commonly caused by bacterial infections, but fungal, viral, and parasitic infections can also trigger it.
Major sources include:
pneumonia (lungs)
urinary tract infections (UTIs),
appendicitis or peritonitis (abdomen)
cellulitis (skin)
meningitis (central nervous system)
High-risk groups for sepsis include the elderly (above 65), pregnant women, and individuals with diabetes mellitus (DM), chronic kidney disease (CKD), obesity, cancer, or weakened immune systems.
Symptoms of Sepsis:
Fever or hypothermia
Confusion or altered mental status
Shortness of breath (hyperventilation)
Rapid heart rate (tachycardia)
Low blood pressure (hypotension)
Decreased urine output
Clammy or sweaty skin
Sepsis rash (discoloration or dark red spots)
Extreme pain or discomfort