Malaria

Malaria

Why it Matters? 

  • India is targeting malaria elimination by 2030, leveraging next-gen vaccines, local innovation, and integrated public health strategies amid persistent challenges from asymptomatic carriers and drug-resistant parasites. 

What You Should Know? 

  • Malaria is caused by Plasmodium parasites and transmitted through bites of infected female Anopheles mosquitoes, as well as through blood transfusions and contaminated needles. 

  • Five species infect humans: P. falciparum (most deadly), P. vivax (relapse-prone), P. malariae, P. ovale, and P. knowlesi. 

  • High-risk groups include infants, children under 5, pregnant women, travellers to endemic regions, and people living with HIV/AIDS. 

  • Symptoms usually appear 10–15 days after the bite, starting with fever, chills, and headache, and can progress to seizures, jaundice, difficulty breathing, and unconsciousness. 

  • Preventive methods include using mosquito nets, repellents with DEET or Icaridin, protective clothing, window screens, and chemoprophylaxis for travellers. 

  • Key vector control strategies are insecticide-treated nets (ITNs) and indoor residual spraying (IRS); resistance to insecticides is a growing concern. 

  • WHO approved RTS,S/AS01 in 2021 and R21/Matrix-M in 2023 for children in high-transmission areas. 

  • WHO's Global Technical Strategy for Malaria (2016–2030) targets a 90% reduction in incidence and mortality, elimination in 35 countries, and prevention of resurgence in malaria-free nations. 

India: 

  • India reduced its malaria burden by over 80% between 2015 and 2023. 

  • India faces a dual species burden of P. falciparum and P. vivax. 

  • New vaccines like RTS,S, R21, and India’s AdFalciVax show promise, though current options target limited parasite stages.  

  • Innovations like transmission-blocking vaccines, mRNA platforms, gene drives, and P. vivax-specific tools are key to achieving the 2030 malaria elimination goal.